The four SE libraries will fit comfortably in 8 gigs of ram. You would probably be ok using just the four SE libraries and your sequencer on a current laptop (note the word "probably"). However, once you start adding Vienna Suite, VE Pro, VI Pro, etc., you will quickly need 12 gigs. As it sounds like you will be eventually looking to add full collections (from your comment regarding "big"), there is no way that will run on an existing laptop as has already been mentioned. Once you start trying to go "big" you will likely quickly find a need for 24 gigs or ram, and a much faster processor. "Small" can be done on a laptop. "Big" still requires a desktop. Those who seek to do "really big" tend to end up either with multiple computers or one computer often with a dual xeon processor and 48 gigs of ram (way out of my budget btw).
As Cyril mentioned, the forthcoming VE Pro coupled with an SSD drive may change things considerably.