I finally had to drop VEPro for the foreseeable future.
I spent the past 4-5 weeks, between projects, working out an alternative to VEPro on the M1 so I can run DP natively, and I've settled on ipMidi and hardware I/O (VEPro or Cantabile hosting on the slave PC). ipMidi is limited to 20 ports, but is far easier to setup and use than RTPmidi.
I'll see what the new year brings from VSL, but I simply could not wait any longer, and had to find a long term, reliable solution due to a heavy workload next year that I need to start preparing for now.
It is worth it just to run DP natively (significantly better performance vs DP-Rosetta). I also can't assume the next version of VEPro will be stable enough for demanding work out of the gate. It could be months before VEPro-native is an option, if the MAS plugin is even available upon first release.
This took a lot of time to reconfigure and test, and time is money. It also comes with a significant hardware investment for the necessary I/O. I know it is "old school", but it works very well.