Same thing for me Dave. I still have the issue and it's not resolved.
This time I loaded up the project and ran absolutely nothing but Studio One. No VE Pro, no internet browser, nothing. Just opened the project and left it looping and it started doing it shortly after.
While the project was now misbehaving, I added a brand new VST3 instance and added a simple woodwinds flute 1 and it does the same thing. I then added a VST2 instance and added the same flute and setup and it doesn't do it.
I then loaded up VE Pro and all of my VE Pro instances are VST3 and they do it as well. I added a VST2 64bit instance with a Synchron player inside of it and it didn't do it.
Perhaps it's a VST3 thing? I am going to copy all the parts to these new VST2 instruments and let them loop for a few hours and see what happens.
Christopher