It depends on how you work. If you like to keep all you wnat to use during programming loaded, it would be not very smart to combine RAM+CPU resource heavy Kontakt + Play Libraries with VSL even if you do not intend to work with Synchron- libraries. Cubase does save .bak-Files regular automatically while you work. If you have a considerable Part of any Play or Kontakt Orchestra-library loaded beside a full VSL-Orchestra you end up waiting half the time you work the long time it takes to save your Cubaseproject bak-file. And do not think your Hardware would be more powerful and will do that much better than mine, (since it is not;😉)
Perhaps it is less tiresome for your Hardware and you if you just load a few seperate specific patches you think you might need to suplement VSL, but this is nothing I would plan for a general template to start working.
With 64GB you can work with nearly the whole Pre-Synchron-VSL-Superpackage in one smart enough if all comes from SSD's But combination with Kontakt or/and Play Libraries in a "template" is more likely makes things much more tedious than helpful.