Within a sequence, the up / down arrows will ony adjust the pitch of highlighted notes when the shortcut button is deselected, then selected again. If the adjusted notes are deselected and other notes are chosen, the shortcut button must again be turned off and on to re-enabe the up / down keys.
Otherwise, the up/down keys choose the channel within the instance, even when the sequencer page has key focus.
Is this a bug or am I misunderstanding something?