With VEP 5 in OS X Maverick the loading times of Play 4.1.6 are very very slow !!
In activity monitor ( disk activity) the loading times do not exceed 50Mo/s , with the samples in SSD Samsung 840 Sata 3 on Apricorn Pci card , and reduce more and more when the patchs take care !!
With the same VEP 5 and SSD Samsung and with Kontakt 5.3.0 the loading times are minimum 256 Mo/s with peaks at 459Mo/s !!
Idem with Spectrasonics Omnisphere and others.
This is on Mac Pro Early 2008 8 cores with 20Go of Ram and no issues with the ram
This as been posted on Eastwest forums also.