I ran a very quick test and I am not sure if my statement about Kontakt inside Cubase or VE PRO stands true. I just tried Kontakt inside VE PRO and inside Cubase 7.5.20. I palyed a pad sound and had a tempo ramp constantly changing tempo. Kontakt inside Cubase was fine until I turned Kontakt's delays on and then the delays sound like they are frying as they keep up with the tempo constant changes. This is probably what I was hearing when I made the previous post. Kontkat inside VE PRO is a little glitchy at my 128 buffer with 2 VE PRO buffers during the tempo change ramp. Bumping it up to 4 buffers stablizes it and throwing on the Kontakt delays creates the frying sound. So barring the tempo delay FX issue during tempo changes I think Kontakt is probably ok inside Cubase.
However...... most of my giant template is inside VE PRO. I hear glitching at tempo changes on more than just Kontakt in my template. I hear it happen on my piano from Addictave Keys and other plugins as well all hosted in VE PRO. Now there is a fair amount of CPU load across these machines and it does appear that these tempo changes in Cubase cause CPU spikes on the VE PRO machines leading to the glitches.
So......Kontakt definitely behaves better inside Cubase (my previous observation might have been related to the delays in Kontakt....I would have to go back and read my post). I think this is more than JUST a Kontakt issue as I can see this problem happening on a machine that does not have any Kontakt's involved. The common denominator looks more like this is a VE PRO issue in my opinion.