I want to also add that when I have loss of midi/audio on a particular slave pc that it usually is just 1 instance inside a bigger metaframe. In other words I might be running 2 or 3 instances with about 14-16 Kontakts in each one. When I notice I am not getting audio/midi on one particular instance usually the 2nd instance with in the same metaframe is still working. So this makes the problem even more confusing as VE PRO 5 obviously has not crashed and the network is still functioning.
I see that several of you are able to cause similar behavioour with EASTWEST PLAY and SPACES, however I do not use either on my machines that have the problem.