At Zero buffers, there is no latency to compensate for!
CPU usage will be a bit higher with 0 latency though, but since the CPU time is yielded back to the scheduler while waiting for data from the VEPro process, the CPU usage is only virtual - adding more plugins in DP should be possible without any noticable increase in total CPU. That being said, processing graph of host of course also comes into play. If plugins and effects are chained after the VEPro plugin, DP has to wait for the VEPro data before continuing with further processing, making this virtual load real :)