I've noticed that when I play legato lines in VI Pro preset 01P LB All Univ Pro matrix my soundcard stops working. Polyphonic legato playing causes this readily. Monophonic legato playing does it too after a while. There's a spike and the audio output ceases even though the MIR engine is still working. I stop and start the MIR engine again to get the soundcard working again.
Marko