Regarding OpenGL.  I just ran the following utility over MRD.  Its an OpenGL feature and benchmarking tool that runs the PC through a bunch of OpenGL.  I did this through MRD.  It ran perfectly fine to completion.

https://gfxbench.com/result.jsp

I'm doubtful that OpenGL has anything to do with the reported crash problems.  That doesn't mean it isn't possible in some situation that the OpenGL tool isn't testing.  I'd like to know more about the windows, OSX and MRD's versions being used that are having problems.

As I mentioned above, I installed UltraVNC on my PC and connected from mac's built in VNC viewer that that also worked perfectly fine, though one thing I did not like is that it does not seem to have a way with that setup to change the resolution of the remote desktop.  My remote PC is using a very small monitor with a very small resolution, so this is far less from ideal.  VNC is capable of using virtual desktop resolutions, so I'm now looking into that, and I found out about another free VNC package with support for both mac and windows, called TigerVNC, which might provide that.  When I have settled on the best solution I'll post here.

spent a lot of time on this tonight and I'm out of it, so this is what I have for now:

1. I can run OpenGL test on my MRD session without problems.
   
   
2. UltraVNC (windows) seems to work very well.  Use built in VNC viewer on Mac or any other VNC client such as tigerVNC, JollyVNC or many others.  
   
   
3. TigerVNC (windows) I could not seem to get my mac to connect to it properly when running as server on windows, but looks like the service wasn't starting, so I coudl probably figure it out if I spent more time but I'm out of time.  UltraVNC works very well too, just use that for the server.
   
   
4. TigerVNC client also works pretty well if you want a dedicated client
   
   
5. I was unable to figure out a way to configure the PC to have a larger desktop size.  The VNC client always wants to use whatever the physical desktop size is on the actual PC.  In my case I have a tiny monitor with tiny resolution, so I could not figure out any way to get VNC to scale up to a nice large desktop on my mac that has 4k monitor.  This is basic behavior of MRD, but apparantly VNC on windows requires the desktop to be the same desktop as the actual machine, which is tied directly to the video card and monitor.  For me that's a deal breaker actually, but maybe someone knows a work around.  I don't and no more time to spend on it.

So bottom line, I think you could use UltraVNC on your pc to get a VNC sessino happening, for free.  I think MRD is a much better solution.  Its not crashing for me.  It would be good to figure out why its crashing for you and not for me, so that maybe you can get to the bottom of it, or more information for VSL.  Nothign else to say, I'm just glad it works for me in MRD because I find VNC to be inferior in every way.  I could live with it if I had to if I could figure out how to enable a larger desktop session from a windows machine.

This might work for the desktop size, but I don't have time to try it now.

https://help.realvnc.com/hc/en-us/articles/360020922991-Why-do-I-see-a-low-resolution-when-connected-to-VNC-Server-for-Windows-on-a-headless-virtual-machine-

what version of MRD?

You aren't using metal.  You will need a Metal capable video card in order to upgrade to Mojave, if you decide to, which by the way I highly reccomend.  When I first got VePro7 I was on Sierra and getting worse performance then VePro6.  It was suggested to me that Mojave and metal would improve things..well I upgraded to Mojave which was one of the best decisions I have made, it improved my macPro 5,1's general benchmark scores by like 15-20% and VePro runs noticeably better then VePro6 in terms of performance on the updated OSX.  part of that may be due to the fact that Mojave requires a Metal video card and takes advantage of that.  I can highly reccomend for your machine that you consider a Metal card such as the RX-580 or closely related.  My mac really gained some performance with that and especially with VePro7.

Now as to whether that would make any difference to your crash problems, is hard to say.  Quite possibly but not neccessarily.  How's that for an answer.

Your PC machine is fine.

There was a verison of MRD a while back that was broken, I can't remember when, but make sure you're running the very latest version of MRD, you're already on the the latest win10.  I'm talking about the MRD client app for OSX.  Make sure its up to date.

I'm starting to think that the issue must be the old video card and not using Metal.  What version of the RX-580 do you have?  I have all my other PCI slots full of SSD drives.  Are you abl to access all your other slots with your graphics card in?  I may just upgrade the card.

I replaced the stock video card with the RX580.  There is one out there that is specfically reccomended by Apple, SapphirePulse.  Google around for that info, I will try to find it later.  There is an RX590 that has come out since then which may have superceded it, and might be better, not sure.  Some people has also used the RX560 for less money.  My RX580 was about $130 as I recall.

With my RX580 video card in place, I still have 3 more slots for whatever and I'm using them all for SSD and soundcard.

I think you said you already upgraded to high Sierra, which included an important firmware update in order to support Metal cards.  For that upgrade, you could not use the RX580 for the firmware update part, because the RX580 does not have boot screen.  What that means is that the screen is blank until its almost fully booted up and then only shows stuff right before seeing your complete desktop.  So prior to High Sierra, you could not perform the firmeware update with this new GPU, you had to keep your old video card installed for that OSX upgrade.  Its not a bad idea to keep your old video card in a box on a shelf for the future just in case.  But apple did improve the Mojave updater, such that it will work with the RX580 and includes yet an additional firmware update...but Mojave actually REQUIRES a metal capable video card such as the RX580. 

Anyway, the Mojave update should work with the new card in place, in fact Apple requires it.  

My experience has been that Mojave is faster and that VePro has also been optimized for Metal in some ways, it has been more efficient, I did performance comparisons between VePro6 and VePro7 at some point and found this to be true.

I do not know whether this will solve your problem with the crashes, but in general I think you will be happy upgrading your video card and upgrading to Mojave honestly.  And maybe that will solve the problem with the crashing.  If not, then we can try to figure out what is different about your system that causes VePro7 to crash under MRD.

Like I said before, make sure you're using the very latest version of MRD available on your Mac.

One other thing to point out, when you move to the Metal card, the mac boots up with a totally black screen until the last minute, which be a little disconcerting.  It still can respond to all the key commands for safe mode, restore more, pram reset, smc reset, etc..all that still works.  Apple made sure the Mojave installer would do its firmware update while looking at a black screen, for example.  It all works, but seems like I had to boot twice or something to get the mojave firmware update to work.  you can google around.  Apple is not supporting our macs for catalina forward.  Some people will figure out how to do it anyway though.  But I doubt there will ever be any more firmware updates for the 5,1 MacPro because of that.  So once you update to Mojave, probably you will not bother going past that ever.  Metal is an improvement for sure, I thnk it was worth the price and I plan to use my 5,1 for at least 3 more years.

Any chance you got to test this with MIR installed?

haven't had a chance yet sorry.