I think I'm doing this w/o MIR in Pro Tools 12: The VEP6 is running as a virtual instrument (really, it's just an Aux return over ethernet) you can bounce it or send it via a hardware output bus or to another internal bus.
I'm also doing this to use a 2nd reverb inside the Apollo Quad via a "Virtual Send" from an Aux channel.
What's your setup? Oe machine or two? Software/host? Are you wanting to use ethernet or are you wanting to connect actual analog and/or digital i/o signals? If you're just doing DSP, perhaps just one extra instance with the DSP alone. Or a second or third machine. I think it can be easily done via ethernet. Just monkeying around with the sends and returns.