@MS said:
With VSTi's it is not a problem, but are you aware of any hosts which support effects with 2ch input / 4ch output plugins?
I'm speculating that Reaper might support effects with 2ch input / 4ch output. I would test to see if it really can, if I knew of a VST 2.4 plugin with 2-in / 4-out to test it on. Do you know of any such plugins (free ones would be nice for this test)?
I have no idea about other DAW's being one way or the other.