Hello,
Are you using VE Pro locally, on a slave?
Have you tried raising the sound card's buffer size?
Also, I use VE Pro on a slave. I had set up VE Pro in the prefs to have 32 MIDI chs. I got the occasional spike. One day, I decided (for another reason) to lower the MIDI chs in the VE Pro settings from 32 > 12, as that is really all I need. Now, i do have a BUNCh of VE Pro instances loaded , but, as a result of doing what I did, my RAM usage went down, Cubase's ASIO performance meter went way down, and no more spikes. The less instances of VE Pro you have, the less of an effect that may have, however.
Cheers.