More often than not I take out some healthy dBs around 2400 and 4500 Hz in narrow bands. This is true for "real" recordings of string-ensembles, too, BTW, where I don't hesitate to reduce this bands by 6 to 8 dB, in case I have an EQ I can rely on. A more advanced concept is to use a dynamic EQ (IOW: a multiband compressor), to tame the shrillness without killing the bite.
/Dietz - Vienna Symphonic Library